Low-calcium dialysate stimulates parathormone secretion and its long-term use worsens secondary hyperparathyroidism.

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Low-calcium dialysate stimulates parathormone secretion and its long-term use worsens secondary hyperparathyroidism.

The long-term clinical effects of the use of a low calcium concentration in the dialysate are largely unknown. For this reason, the influence of low-calcium dialysate on parathyroid hormone (PTH) secretion in hemodialysis patients and its long-term effect on the severity of secondary hyperparathyroidism were studied. In 35 hemodialysis patients, the dialysate calcium concentration was lowered f...

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Impact of vitamin C on parathormone secretion in patients on hemodialysis with secondary hyperparathyroidism

Secondary hyperparathyroidism is a complication of chronic kidney disease, and it develops due to abnormal regulation of calcium and phosphate homeostasis (1). Various factors interact in its development. They are consist of decrease kidney synthesis of 1,25-dihydroxyvitamin D, the, phosphorus retention and impaired calcemic response to parathyroid hormone (1,2). Hence, increasing of parathormo...

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How do we have to use the calcium in the dialysate to optimize the management of secondary hyperparathyroidism?

Hyperparathyroidism, adynamic bone disease, osteoDialysate Ca concentration (dCa) was one of the first malacia and b2-microglobulin amyloidosis are all conparameters which renal physicians studied to deal with ditions involving bone that may be observed in chronic hyperparathyroidism. Fournier et al. observed that the renal failure patients. Their relative incidence varies use of a dialysate Ca...

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Ovariectomy worsens secondary hyperparathyroidism in mature rats during low-Ca diet.

Estrogen deficiency impairs intestinal Ca absorption and induces bone loss, but its effects on the vitamin D-endocrine system are unclear. In the present study, calciotropic hormones levels, renal vitamin D metabolism, 1,25-dihydroxyvitamin D3 [1,25(OH)2D3]-dependent intestinal calcium absorption, and bone properties in 3-mo-old sham-operated (sham) or ovariectomized (OVX) rats fed either a nor...

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ژورنال

عنوان ژورنال: Journal of the American Society of Nephrology

سال: 1995

ISSN: 1046-6673,1533-3450

DOI: 10.1681/asn.v61132